植物脂质组学分析

      植物中本身独特的生理性质要求采用特定的脂质提取方案，以获得准确反映内源条件的生物学上有意义的脂质组（Lam SM et al., 2017）。此外，植物还含有与动物内源性不同类型的膜脂质（Cheong WF et al., 2014）。我们对各种植物种类有着丰富的分析经验，从常用的模式植物拟南芥到主要的粮食作物水稻，小麦和大豆等（Nakamura Y et al., 2009; Kanehara K et al., 2015; Li QT et al., 2017; Patkar RN et al., 2012; Tian H et al., 2016）。

参考文献

Cheong WF, Wenk MR, Shui G. Comprehensive analysis of lipid composition in crude palm oil using multiple lipidomic approaches. J Genet Genomics. 2014; 41(5): 293-304.

Nakamura Y, Koizumi R, Shui G, Shimojima M, Wenk MR, Ito T, et al. Arabidopsis lipins mediate eukaryotic pathway of lipid metabolism and cope critically with phosphate starvation. Proc Natl Acad Sci U S A. 2009; 106(49): 20978-83.

Kanehara K, Yu CY, Cho Y, Cheong WF, Torta F, Shui G, et al. Arabidopsis AtPLC2 Is a Primary Phosphoinositide-Specific Phospholipase C in Phosphoinositide Metabolism and the Endoplasmic Reticulum Stress Response. PLoS Genet. 2015; 11(9): e1005511.

Li QT, Lu X, Song QX, Chen HW, Wei W, Tao JJ, et al. Selection for a Zinc-Finger Protein Contributes to Seed Oil Increase during Soybean Domestication. Plant physiology. 2017; 173(4): 2208-24.

Patkar RN, Xue YK, Shui G, Wenk MR, Naqvi NI. Abc3-mediated efflux of an endogenous digoxin-like steroidal glycoside by Magnaporthe oryzae is necessary for host invasion during blast disease. PLoS Pathog. 2012; 8(8): e1002888.

Tian H, Lam SM, Shui G. Metabolomics, a Powerful Tool for Agricultural Research. Int J Mol Sci. 2016; 17(11).